A series of 135 cases of pterygium observed at the Eye Dept, in the National Medical Center from April 1963 to May 1966, were treated with thio-tepa after the surgical removal and were studied clinically in regard to the incidence of the recurrence.
Among the total series, only one case showed no response to the thio-tepa instillation and the recurrence persisted.
There was a case of allergic response to the thio-tepa, which has not been found in any reports known.
No serious local or systemic toxcity or any sequelae such as corneal damages, defective vision or the interference with wound healing could be observed,
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